We imputed genome-wide structural variants (SVs) and variable number tandem repeats (VNTRs) from a long-read sequencing-based reference panel into 2,693 unrelated individuals of European ancestry with 3,357 brain transcriptomes. We performed a molecular quantitative trait locus (xQTL) analysis for a comprehensive mapping of SV and VNTR associations with transcription level (eQTL), alternative splicing (sQTL), and polyadenylation (apaQTL) in cis region. This portal includes summary statistics and interactive visualizations of cis-xQTLs of SVs and VNTRs.
• Shuli Liu (SV & VNTR-xQTL mapping, documentation)
• Junren Hou (online tool development & maintenance)
• Jian Yang (conceptualization, supervision, documentation)
We thank the Westlake University High-Performance Computing Center for hosting the portal and summary data. The portal adapts source code from PheWeb.
If you have any question, please send an email to Jian Yang at jian.yang@westlake.edu.cn or Shuli Liu at liushuli@westlake.edu.cn.
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This site was built with PheWeb v1.3.15.
All positions are on GRCh38.