gsMap Command Line Alphabets

Synopsis

usage: gsmap [-h] [--version] {run_find_latent_representations,run_latent_to_gene,run_generate_ldscore,run_spatial_ldsc,run_cauchy_combination,run_report,format_sumstats,quick_mode} ...

Description

gsmap: genetically informed spatial mapping of cells for complex traits.

Options

-h, --help

Show this help message and exit.

--version, -v

Show program’s version number and exit.

Subcommands

format_sumstats

Convert GWAS summary statistics into the format that gsMap can recognize.

run_find_latent_representations

Find the latent representations of each spot by running GNN-VAE.

run_latent_to_gene

Generate gene specificity scores (GSS) for each spot.

run_generate_ldscore

Generate LD scores for each spot.

run_spatial_ldsc

Perform LDSC for each spot.

run_cauchy_combination

Perform cauchy combination test for each annotation.

run_report

Generate gsMap report.

quick_mode

Run entire gsMap Pipeline.

create_slice_mean

Create Slice Mean using multiple slices.